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Preclinical CagriSema data suggests it may preserve energy expenditure by maintaining mitochondrial function in skeletal muscle, which could theoretically support better muscle preservation over time

The dopamine and serotonin modulation aspects suggest potential applications beyond physical nerve repair

Immunofluorescence staining also showed a marked increase in the number of Ki-67-positive cells and a decrease in the nuclear content of -H2AX and P21 after FOXO4-DRI treatment (Figures 4B,C)