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To provide insight into caviar/roe metabolome heterogeneity in the context of interspecies, gender-related, and infraspecific variability, different models of unsupervised and supervised chemometric tools were employed, exemplified by principal component analysis (PCA), hierarchical cluster analysis (HCA), and orthogonal partial least squares discriminant analysis (OPLS-DA)

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Subjects were enrolled at the Department of Transfusion Medicine of the Trieste University Hospital and signed written informed consent to participate to the study in accordance with the recommendations of the declaration of Helsinki and the Italian law DL n 675 of the 31-12-1996