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Chronic use of NSAIDs like ibuprofen is a leading cause of gastric ulcers and GI bleeding

Cell Cycle 16:12431251 Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM et al (2014) NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING