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However, much of the research has illustrated that such an effect is a negation of caffeines ability to raise blood pressure rather than an ability of L-theanine to take a persons blood pressure down below its normal resting state.26 Also, in some research looking at L-theanine in isolation (or, more specifically, in mango sorbet), no effect on blood pressure was observed.27 It appears that L-theanine should be mostly safe for most people, but its always a good idea to talk to your doctor before introducing any new supplement into your regimen

Your doctor may choose to start you on a short-term medication as a supplement to these changes

Conflict of interest CM, LR-P, JE, and SH are employees and HK and SK are scientific cofounders of NEUmiRNA Therapeutics, a biopharmaceutical company developing RNA-based therapeutics for neurological disorders

(2011) 300:G53846