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In tomato, QTLs on chromosomes 2 and 12 have been linked to variation in fruit size accounting for up to 20% of phenotypic variance and fruit shape, including obovoid forms, with effects confirmed across generations (Adhikari et al

Modulation of insulin sensitivity by insulin-degrading enzyme

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reported that carrying of the GSTM1 null genotype, the GSTP1 A/B or B/B genotype, and the GSTA1 A/B or B/B genotype is associated with higher risk for MASLD development, as these genotypes show lower substrate affinity or lower hepatic expression compared to wild-type genotypes (Oniki et al