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This effect may slightly lower the pills ability to prevent pregnancy

Disruption of the PDIA5-ATF6 axis restores sensitivity in imatinib-resistant leukemia cells, highlighting ATF6 as a therapeutically actionable target

2025;doi:10.1111/dom.16152

An outward-facing aromatic amino acid is crucial for signaling between the membrane-spanning and nucleotide-binding domains of multidrug resistance protein 1 (MRP1