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Haugstvedt JR, Berger RA, Nakamura T, Neale P, Berglund L, An KN

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Nicotinamide riboside (NR) given to C57BL/6J mice at about 2 years old led to a most important 5% increase in lifespan [4]

While the threshold level could be extended only to 35 min with hydroxocobalamin (300 mg/kg i.v.) the protective action of sodium thiosulphate (100, 500 and 1000 mg/kg i.v.) persisted dose dependently for about 1, 2 and 4 h, respectively