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10.1016/j.bcp.2022.115182 21 ChenP.TorralbaM.TanJ.EmbreeM.ZenglerK.StarkelP.et al (2015)

Marston in the Eastern District of Pennsylvania, consolidates claims that GLP-1 drugs caused NAION non-arteritic anterior ischemic optic neuropathy, a sudden, painless form of vision loss sometimes called "eye stroke." A July 2024 study in JAMA Ophthalmology found that semaglutide users faced a 4.28x increased risk of NAION among diabetics and a 7.64x increased risk among weight-loss patients

The combination of a glucagon-like peptide-1 receptor (GLP-1) agonist plus basal insulin offered the ideal triumvirate, according to Laura Young and John Buse from the University of North Carolina, USA, in an accompanying commentary to the meta-analysis [2]