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PMID: Summary Keywords biologic therapy, early psoriatic arthritis, GLP-1 receptor agonists, inflammation, metabolic syndrome, psoriasis Citation Ciancio G, Maranini B, Sandri G, Amati G, Bortoluzzi A, Silvagni E, Govoni M and Giuggioli D (2026) Glucagon-like peptide-1 receptor agonists in psoriasis and psoriatic arthritis: emerging evidence and future research opportunities

Circulating metabolic hormones, including leptin, insulin, adiponectin, and ghrelin, are transmitted from the periphery to the ARC in hypothalamus by passing across the median eminence, regulating long-term energy metabolism [37]

The most common ones include brief lethargy after an injection, slight swelling or tenderness at the injection site, and occasional mild digestive upset

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