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Clinical research has shown that, when combined with a reduced-calorie diet and increased physical activity, semaglutide can lead to significant weight loss

Lilly's ads are based on a head-to-head study comparing its Zepbound versus Wegovy that was published in the New England Journal of Medicine in May 2025 , before the higher dose of Wegovy was on the market

These countries may also require certain documentation, such as a medical certificate, so its important to check

Patients without commercial insurance can use the Eli Lilly savings card to save up to $463-$647 per fill, potentially bringing costs down significantly