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For women already dealing with fatigue and hormonal shifts, these risks can feel magnified

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2.3 Metabolic assessment Mice were singly housed in cages automatically collecting food and water intake data (PhenoMaster, TSE Systems)

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Mechanistically, statins altered the bile-acid pool (notably lowering ursodeoxycholic acid, UDCA), which reduced signaling through the TGR5 receptor on intestinal cells, leading to less GLP-1 release

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Less myostatin activity makes it easier to hold onto muscle during a deficit

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