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It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile

The use of fertilizers containing Zn at low concentrations leads to the activation of antioxidant enzymes, non-oxidizing metabolism, as well as carbohydrate metabolism to reduce oxidative damage 54

This helps promote liver health and function

Compromised oxygen delivery due to nutrient deficiencies or physiological damage can harm the brain and result in intellectual impairment