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cruzi epimastigote can avoid heme toxicity, and instead use it as a signaling molecule for its proliferation in the insect midgut (Lara et al., 2007

However, widespread urticaria, mucosal involvement, or systemic symptoms such as dyspnea warrant immediate evaluation

When the amount of non-ionic surfactants and cholesterol increases, the amount of the hydrophobic domain and the number of niosomes produced raises and hence increases in entrapment efficiency and particle size 56,57

Yet, we showed a significant and relatively large effect of NPW on striatal DA (Cohens d = 1.05) that could be clinically meaningful and merits further investigation