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It was FDA-approved for obesity in 2014

Sedentary: 0.8 grams per pound of goal body weight Moderately active: 0.9 grams per pound of goal body weight Resistance training: 1.0+ grams per pound of goal body weight Example: Goal weight of 150 pounds with moderate activity = 135 grams protein daily Distribute protein across 5 to 6 smaller meals rather than 2 or 3 large ones

These variations may lack the same level of safety and efficacy data as FDA-approved products

The TRIUMPH-4 Phase 3 data provides the most current safety information: Nausea: 38.1% (9 mg) to 43.2% (12 mg) versus 10.7% placebo Diarrhea: 34.7% (9 mg) to 33.1% (12 mg) versus 13.4% placebo Constipation: 21.8% (9 mg) to 25.0% (12 mg) versus 8.7% placebo Vomiting: 20.4% (9 mg) to 20.9% (12 mg) versus 0% placebo Decreased appetite: 19.0% (9 mg) to 18.2% (12 mg) versus 9.4% placebo The pattern is clear