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Peak Nausea Timeline: Days Two Through Five Most people reach peak nausea symptoms between day two and day five after their semaglutide injection

Future multicenter studies with longer follow-up periods are needed to validate these findings and better evaluate the long-term benefits and limitations of this treatment approach

People with low B12 levels, fatigue, dietary restrictions, absorption issues, or symptoms linked to deficiency may benefit after assessment

Given the rapid and increasing uptake of GLP1Ra-based therapies, coupled with the knowledge gap surrounding their impact on clinically relevant bone outcomes in older adults, we conducted an exploratory post hoc analysis of a pilot trial to explore the impact of 20 weeks of semaglutide use on bone density and turnover in older adults with overweight or obesity