glutathione reduction Oxidation-reduction pathway of reduced (GSH) and oxidized Cyclic(γ Glutathione reductase - Wikipedia

However, when supplementation is discontinued: Melanin production may gradually return to normal levels

Optional: GHK-Cu nasal spray 200 mcg twice daily as a systemic supplement

Nutrients , 15(20), 4378

In vitro and animal studies have found that lipoic acid exhibits immunomodulatory properties through mechanisms that stimulate the production of cyclic AMP (cAMP) (90, 91) a central regulator of innate immune functions and inhibits the migration of immune cells into the brain and spinal cord (92), possibly by decreasing endothelial expression of cell adhesion molecules, inhibiting expression of enzymes like matrix metalloproteinases (MMP), and/or reducing the permeability of the blood-brain barrier (87, 89, 93, 94)