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NICE guidelines emphasise the importance of holistic diabetes care that addresses both physical and psychological wellbeing, recognising that mental health significantly impacts diabetes self-management and outcomes

In other cases, the in silico risk assessment can inform and direct the proper in vitro immunogenicity assay

GLP-1 receptor agonists have demonstrated the ability to increase insulin secretion, inhibit glucagon release, and slow gastric emptying, offering powerful benefits in controlling appetite, regulating blood sugar levels, and managing body weight

To effectively develop a PBPK model for studying mechanism-of-action-mediated DDIs, it is essential to carefully assess the extent to which these mechanisms impact pharmacokinetics