Patients received an initial dose of either 1 mg, 2 mg, or 4 mg of retatrutide and subsequent doses of either 1 mg, 4 mg, 8 mg, or 12 mg, or they received a placebo throughout the 48 weeks of the study
Dariush Mozaffarian 1, Monica Agarwal 2, Monica Aggarwal 3, Lydia Alexander 4, Caroline M Apovian 5, Shagun Bindlish 6, Jonathan Bonnet 7, W Scott Butsch 8, Sandra Christensen 9, Eugenia Gianos 10, Mahima Gulati 11, Alka Gupta 12 13, Debbie Horn 14, Ryan M Kane 15 16, Jasdeep Saluja 17, Deepa Sannidhi 18, Fatima Cody Stanford 19 20, Emily A Callahan 1
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If you have a family history of cardiovascular disease, existing risk factors like high blood pressure or elevated cholesterol, or a history of cardiac events, discuss the cardiovascular implications of discontinuation specifically with your provider