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Jaeschke H, Williams CD, McGill MR (2012) Caveats of using acetaminophen hepatotoxicity models for natural product testing

Prevalence of cataracts in a population-based study of persons with diabetes mellitus

Due to a large 44-base pair deletion, isoform B is non-functional, while isoforms A and X1 exhibit enzymatic activity

the AGE-RAGE signaling, which induces axonal atrophy through p38 MAPK activation (Sango et al., 2025), and the PKC- activation, which impairs nerve blood flow via endothelin-1 overexpression ( Hyperglycemia-induced mitochondrial dysfunction in neuronal and Schwann cells leads to excessive O 2 production at complex I and III of the ETC, which initiates a cascade of injury through four primary mechanisms (Wu L