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, 42 , 189-197, Bollu, A., Schepers, H., Klcker, N., Erguven, M., Lawrence-Drner, A., and Rentmeister, A

Researchers derived this synthetic peptide from a naturally occurring protective protein found within gastric juice

GSTP1*B is an allele in which a single nucleotide (AG) substitution at position 313 substantially diminishes catalytic activity [64]

The growth signal is therefore indirect and paracrine : activating those receptors releases IGF-1, IGF-2, keratinocyte growth factor and nitric oxide , and those mediators drive crypt-cell proliferation, increased villus height, deeper crypts and increased intestinal and portal blood flow [1] [5]