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On the other hand, semaglutide could increase the pathways involved in starch and sucrose metabolism, porphyrin metabolism, and degradation of flavonoids while decreasing the metabolism of nucleotide, such as purine pyrimidine metabolism and pyrimidine metabolism in mice with PCOS (Figure 5C and D)

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Muscogiuri G., DeFronzo R.A., Gastaldelli A., Holst J.J

The magnitude of the AG fitness effect was determined by (a) subtracting the AG fitness scores in the uninfected library from the infected libraries to assess whether AGs changed host sensitivity to phage infection, and (b) subtracting the AG fitness scores in the baseline library from the uninfected libraries to assess whether AGs change host fitness directly