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A Th17 Cell-Intrinsic Glutathione/Mitochondrial-IL-22 Axis Protects against Intestinal Inflammation

The authors reported a pharmacokinetic profile consistent with extended-interval administration and described the observed tolerability findings in the context of the broader incretin-agonist class

Elevated expression of M1 macrophage-specific molecules and reduced expression of M2 macrophage-specific molecules support the shifting of M1/M2 macrophage polarization in the direction of the inflammatory M1 phenotype in a variety of neuropathic pain types (Tripathi et al