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demonstrated that reducing Gln levels, inhibiting the transmembrane transport of Gln (using V-9302), or blocking Gln metabolism (with CB-839) markedly decreased mesothelioma cell proliferation, spheroid formation, invasion, and migration

Biomedicines 10:3070

Key Point: Weight loss medications, combined with a healthy lifestyle, can lead to significant weight loss and reduce risks associated with obesity, such as heart disease and type 2 diabetes

GHK and Oncogene Regulation Early-stage studies have proposed that GHK, particularly in copper-bound form, may participate in the modulation of tumor suppressor genes and growth regulation