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WADA currently employs two types of assay when testing for GH abuse: the so called Differential Isoforms Immunoassay that determines the ratio between the 22 kDa rhGH isoform and endogenous isoforms

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Simultaneously, disturbed level of miR-21 was observed in diverse neuropathic pain models (Zhong et al., 2019) where it targets metalloproteinase-3 (TIMP3) and chemokines C-C motif ligand 1 (CCL1) that consequently evoke cytokine production of TNF-, IL-1, and IL-6 and aggravate neuroinflammation

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