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We acknowledge the Key Discipline Construction Project (2023-2025) of the Three-Year Initiative Plan for Strengthening Public Health System Construction in Shanghai (GWVI-11.1-35 to H.H.), Shanghai Clinical Research Center for Gynecological Diseases (22MC1940200 to H.H.), Shanghai Urogenital System Diseases Research Center (2022ZZ01012 to H.H.), Shanghai Frontiers Science Research Center of Reproduction and Development (to H.H.), the National Key Research and Development Program of China (2024YFA180300 to G.D.), and the Fund of Fudan University and Caoejiang Basic Research (24FCA14 to G.D.)
This allows for smaller injection volumes but requires more precise measurement
The Science Cagrilintide is a long-acting analogue of amylin, a hormone naturally released by the pancreas alongside insulin after meals
The binding was done in end-over rotation at 4 C for 3 h
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