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Seek medical attention if : Bruising is severe, extensive, or disproportionate to the injection New bruises appear spontaneously at non-injection sites Bruising is accompanied by prolonged bleeding, petechiae (pinpoint red spots), or mucosal bleeding (nosebleeds, gum bleeding) Signs of infection develop (increasing pain, warmth, redness, swelling, or discharge) Bruises fail to resolve after 34 weeks Documentation : Keep a record of injection sites and any bruising patterns

PLoS ONE 3:e1944 Srinivasan R, Ratiney H, Hammond-Rosenbluth KE, Pelletier D, Nelson SJ (2010) MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis