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Similarly, the SwedeHF study, comprising 4942 patients, found that female sex, nonischemic causes, higher blood pressure, and shorter heart failure duration were predictors of HFimpEF 24

Variants in GLP1R (rs6923761) and GIPR (rs1800437) can correlate with differential GLP-1 agonist efficacy and tolerability, information that should be interpreted with a qualified healthcare provider to inform whether adding inositol supplementation is warranted

Weight loss itself reduces pressure on digestive organs

The drug mimics the effects of these incretin hormones, enhancing insulin secretion, and promoting satiety, leading to reduced food intake and potential weight loss