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#PBPK #MechanisticIVIVC #Biopharmaceutics #ModelInformedDrugDevelopment #VirtualBioequivalence #DrugDevelopment #Pharmacokinetics #GastroPlus #Simcyp #PKSim #ComputationalPharmaceutics #PharmaceuticalSciences To view or add a comment, sign in 23,126 followers
GR can perform its enzymatic activity in the cytoplasm, but also in the ER and within lysosomes, mitochondria and the nucleus
De Flora et al., 2020
Despite the fact that exercise is a potent inductor of the HSP response [89], local and systemic inflammatory lesion leads to a reduction in intracellular HSP70 levels, which may impair tissue readjustment [30, 89, 90]
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