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For advanced cases, consultation with oncologists or cancer surgeons is essential

For mouse serum collection, the animals were anaesthetized with isoflurane, and blood was collected via the retro-orbital venous sinus into BD microtainer tubes (BD, 365967)

Predrag Sikirics group (School of Medicine, University of Zagreb, 1991 ) Most common experimental dose in animal studies: 10 g/kg intraperitoneally or per os, daily Standard targeted pathways: VEGFR2 angiogenesis, NO synthase , 5-HT2A serotonin receptor, dopamine D2 receptor Clinical program in Croatia halted at Phase 2 (Crohns disease) WADA Prohibited List: added in 2022 to category S0 (Non-Approved Substances) Reference sources (PubMed) Sikiric P