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In a study of the combined administration of clopidogrel (300 mg on the first day and 75 mg on the second to third day) and repaglinide (0.25 mg as a single dose), the geometric mean area under the concentration-time curve (AUC 0- ) of repaglinide was increased 3.95.1 fold, and the peak plasma concentration (C max ) was increased 2.02.5 fold when compared with the control [7]