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Epithalon (also known as Epitalon) is a synthetic tetrapeptide investigated in aging-related research, focusing on cellular stress responses, gene expression patterns, and circadian-associated biology in preclinical models

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However, none of the published protocols explicitly implement anti-adaptive strategies, despite an estimated ketogenic metabolic advantage (100300 kcal/day), context-dependent and more consistently observed in longer trials and during weight-maintenance settings