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Collectively, these findings suggest that iron dyshomeostasis orchestrates immune dysfunction through multiple converging pathwaysincluding microglial and astrocytic activation and central T cell infiltration

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Lipoic acid has also been shown to improve nitric oxide (NO)-dependent vasodilation in aged rats by increasing PKB/Akt-dependent phosphorylation of endothelial NO synthase (eNOS) and eNOS-catalyzed NO production (47)

Thymosin 4 activates integrin-linked kinase and promotes cardiac repair. Nature 2004