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Patients reported that their daytime voiding frequency decreased from 9.5 times to 7.5 times per day, and nocturia (nighttime urination) resolved in 7 of 19 patients taking dulaglutide compared to only 1 of 16 patients on placebo

Three subjects (11.5%) changed from prefail to normal

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However, its angiogenic properties raise legitimate safety considerations, suggesting that indication-specific developmentfavoring acute or localized applicationsmay be more appropriate than chronic systemic exposure