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doi: 10.1021/acs.est.3c03829 [DOI] [PubMed] [Google Scholar] 243.Huang W, Wen L, Tian H, et al

They are metabolised via the thiopurine S-methyltransferase (TPMT) enzyme, and polymorphisms in the gene encoding this enzyme can lead to variable enzyme activity and potential toxicity

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Serotonin and migraine: a reconsideration of the central theory