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Researchers developed a synthetic version of IGF-1 called IGF-1 LR3 (long arginine 3-IGF-1) so they could study the actions of this hormone for longer periods

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Given that there is no placebo-controlled human data, no established dose, and a mechanism whose foundational papers were retracted, an absence of noticeable effect is fully consistent with the current evidence it does not necessarily indicate a defective product, the wrong route, or an insufficient duration