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The documented mechanisms are: VEGF stimulation in dermal fibroblasts that supports the microvascular network feeding the follicle, collagen and glycosaminoglycan synthesis at the follicular basement membrane, anti-inflammatory signaling that calms the chronic micro-inflammation associated with androgenetic alopecia, and direct follicular signaling that extends the anagen growth phase

If medication is needed, discuss with your prescriberoptions may include antiemetics, but these have their own safety considerations (domperidone has cardiac risks and is only for short-term use

On the other hand, preclinical studies report that the activation of MC3R and MC4R by melanotan peptides can result in significant appetite suppression, anorexia, and weight loss [22]

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