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And most dont offer much beyond basic salt and potassium

On the contrary, MTX + carnitine samples (group 6) showed significant protective efficacy on renal parenchyma with almost intact kidney corpuscles (star), mild focal records of tubular epithelial damage (red arrow) alternated with obvious integral tubular segments (black arrow) and minimal interstitial infiltrates

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Some patients benefit from combination T4/T3 therapy, though evidence supporting superiority over levothyroxine monotherapy is limited