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KEGG classification and enrichment analysis (Figure 5E) revealed that the metabolic reconfigurations predominantly affected Metabolic Pathways, Biosynthesis of Secondary Metabolites, and Microbial Metabolism in Diverse Environments, highlighting the extensive influence of GR on the bacteriums metabolic processes

25 The main pathway target of omega-3, which is also linked to the inflammatory hypothesis of depression, 26 is the arachidonic acid inflammatory pathway