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Vitamin B12 is very important for your body to function properly, and individuals who are following a vegan or vegetarian diet are likely to have deficient B12 levels because it is obtained from animal products

Even if you meet the BMI criteria, certain medical conditions may prevent you from taking specific weight loss medications

Glucagon agonism, counterintuitively, helps by enhancing fat metabolism (lipolysis and fatty acid oxidation), reducing liver fat, and improving metabolic flexibility

In conclusion, while the jurys still out on orforglipron, it promises to broaden access to GLP-1 therapy, making it a potentially valuable addition to our therapeutic arsenal