constipated on glp 1 Starting GLP-1 and feeling constipated? 👀 You're not alone. This can happen in the early stage of treatment — and it's exactly why doctor guidance matters from day one 💚 At our GLP-1 Gut Side Effects: Bloating

Apply light pressure to the site with a clean gauze pad for a few seconds, without rubbing

32,33 Under physiological conditions, besides the paracrine secretion pathway in the gastrointestinal tract, most endogenous GLP-1 in circulation is locally deactivated by DPP-4 and the liver, 34 making it difficult to directly enter the CNS through the blood-brain barrier

Nat Rev Immunol (2003) 3(11):90011.10.1038/nri1226 7 BrooksAJWatersMJ

Otros efectos secundarios son el eritema que aparece tras la primera o la segunda semana de tratamiento, la xerosis de piel y mucosas, el prurito intenso, especial-mente del cuero cabelludo, y la estomatitis