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When the hormone or the receptor agonist binds to it, a series of cascade effects occur, eventually leading to the release of Ca2+

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By bridging this gap and characterizing CTB-enriched clusters on live cells, we speculate that on length scales of order 10100 nm, the cytoskeleton may not dramatically change bulky protein composition beyond that of equilibrium domains, supporting the use of actin-free systems like GPMVs to measure the lateral distribution of crowders 17,52