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VG161 activates systemic antitumor immunity in pancreatic cancer models as a novel oncolytic herpesvirus expressing multiple immunomodulatory transgenes

72 hpf and 7 dpf were selected as the exposure ages because they correspond to specific events in visual system development, with the 70-74 hpf developmental timepoint being associated with functional retinal transduction pathways 44 , innervation of the optic tectum 45 , and the onset of visually guided behaviors 43

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Thus, considering BPC 157/Parkinsons disease/Alzheimers disease, BPC 157 therapy was effective in Parkinsons disease models, and it counteracted parkinsonogenic neurotoxin MPTP-induced tremor, rigor, akinesia, and gastric lesions and counteracted mortality in mice, reserpine-induced akinesia, catalepsy, hypothermia, and catalepsy induced by neuroleptics or NOS-blocker L-NAME application [198,199,200]