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LEP promotes tumor growth by stimulating angiogenesis [47]

IDF diabetes atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045

Mc4r agonism promotes durable weight loss in patients with leptin receptor deficiency

In a small study of 21 healthy-weight individuals who consumed a MedDiet for 3 days, then a Canadian diet [reflecting the average Canadian dietary intake, which would be considered a Western diet (180)] for 13 days, followed by a MedDiet for an additional 3 days, circulating SCFAs and branched-chain fatty acids were not significantly altered by the first MedDiet intervention, but propionate, valerate, isobutyrate, and isovalerate were increased by the Canadian diet, then decreased after the second MedDiet (65)