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Women Tend to Lose More Weight on GLP-1s Than Men We looked at lots of different factors that might be plausibly associated with efficacy of these products, and sex was the only one of the five or six that we looked at where we found significantly different effects, says coauthor Caleb Alexander, MD, an internist, epidemiologist, and co-director of the Center for Drug Safety and Effectiveness at Johns Hopkins Medicine in Baltimore

At the habits level, the combination of strength training and aerobic activity is key

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And, when users stop, many begin regaining weight within two months