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In glycolysis, NAD+ accepts electrons during the oxidation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate, a reaction catalyzed by glyceraldehyde-3-phosphate dehydrogenase that generates NADH while enabling glucose catabolism to proceed

When the oxidative stress [which is defined as an imbalance that leads to cell and tissue damage] becomes too high in the body, then we start seeing all kinds of diseases: Obesity, diabetes, hypertension, heart disease, metabolic disorderswe can even go as far as cancer, he states