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CC 50 values measured for atpenin A5 based on MTT and CTG closely mimic the IC 50 , with 3.6 M (MTT) and 1.0 M (CTG), respectively

Solutions include using smaller vials matched to your dose level, splitting a large vial into smaller sterile vials after reconstitution, or starting with a higher dose that uses the vial within 28 days

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As neither normal ducts nor PanIN 3 lesions nor pancreatic carcinoma cells express GLP1R in a measurable way, the GLP1R in PanIN 1/2 may be understood as a rare and probably transient phenomenon that is not necessarily involved in neoplastic transformation