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Notably, certain plant-derived metabolites activate neuroprotective signaling pathways, such as the MAPK/NF-B system, (Md et al., 2021), and interact with estrogen receptor beta (ER), a known regulator of synaptic plasticity and neuroprotection (Cardona-Gmez et al., 2006)

The treatment is beneficial for individuals dealing with chronic fatigue, exposure to heavy metals or environmental toxins, poor immune function, or issues like brain fog and sluggishness

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A randomised, double-blind, placebo-controlled trial is the highest-quality study design for a single trial