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And the four horsemen that you laid out so well, cancer, neurodegenerative disease, cardiovascular and metabolic dysfunction, all play into that, that we could actually prevent these

T cell stimulation activates the PI3K and Akt pathways, which are upstream regulators of mTOR that affect cell metabolism and glucose uptake that drive anabolic pathways required for cell proliferation (Zhang et al., 2011

In vivo exposure of mice to UV-B has not only induced subcapsular cataract, but also cortical and nuclear cataract (150)