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(2) AHK-Cu (Copper Tripeptide-3) Full name: Alanyl-Histidyl-Lysine Copper Complex Chemical formula: CHCuNO Structural characteristics: Alanine (Ala) replaces glycine to form Ala-His-Lys-Cu complex

Additional studies show BPC-157 modifies signaling of focal adhesion components such as focal adhesion kinase (FAK) and paxillin, critical for cell migration, attachment, and wound closure

By limiting the most probable DPP-8-selectivity imparting modification points in DPP-8/9 inhibitors to areas of space that are topologically similar to the piperazine ring, this strategy may serve as a useful platform for developing future selective DPP-8 inhibitors, including novel chemotypes

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