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Available from: 18 Jefferies, 2023
While human data is more limited, the clinical picture is consistent: semaglutide users who experience persistent GI issues often show lower microbiome diversity on stool testing than those who tolerate the medication well
The FDA's adverse event database documented more than 990 reports linked to compounded semaglutide and more than 730 linked to compounded tirzepatide as of May 31, 2026, per publicly available FDA safety communications
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